Affiliated Staff Directory

Keith Matthews

Research Interests

In general terms, my interests include the psychology and biology of psychiatric disorders, particularly the role of early experience and environmental adversity in creating 'vulnerability'. Specific current interests include the neuropsychopharmacology of Attention Deficit Hyperactivity Disorder in children and adolescents and improving the management of chronic, treatment-resistant mental health problems in adults - notably depression and Obsessive Compulsive Disorders. I am also interested in identifying the mechanisms by which environmental and social influences impact upon vulnerability to psychiatric disorder and how they determine responses to treatment interventions.

Recent health-related publications

Matthews, K., Robbins, T.W., Everitt, B.J. and Caine, S.B. (1999) Repeated neonatal maternal separation alters intravenous cocaine self-administration in adult rats, Psychopharmacology, 141:123-134.

Matthews, K. and Eljamel, M.S. (2002) The status of neurosurgery for mental disorder (NMD) in Scotland, British Journal of Psychiatry.

Matthews, K. and Robbins, T.W. (2002) Early experience as a determinant of adult behavioural responses to reward: the effects of repeated maternal separation in the rat, Neurosciences and Biobehavioural Reviews.

Current grants

Matthews, K. (2003) A survey of patients prescribed long-term antidepressants in Primary Care, Chief Scientist Office.

Matthews, K. (2000) Structured group behavioural psychotherapy for depressive disorder: a prospective, randomised, controlled trial of clinical efficacy and cost-utility, Chief Scientist Office, Scottish Executive.

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